Comparisons

Product Comparison

T3 (Liothyronine) vs T4 (Levothyroxin)

T3 (Liothyronine, active) versus T4 (Levothyroxine, prodrug). Direct action versus liver conversion.

T3 (Liothyronine) vial Cutting

T3 (Liothyronine)

Form
Tab
Sizes
25mcg × 100 Tabs, 40mcg × 100 Tabs, 100mcg × 100 Tabs, 20mcg × 100 Tabs, 50mcg × 100 Tabs, 50mcg × 50 Tabs
Price (per bottle)
20 - 155 EUR
Full detail page
T4 (Levothyroxin) vial Cutting

T4 (Levothyroxin)

Form
Tab
Sizes
40mcg × 100 Tabs, 100mcg × 50 Tabs, 100mcg × 120 Tabs, 200mcg × 100 Tabs
Price (per bottle)
32 - 115 EUR
Full detail page

By the numbers

Number of sizes T3 (Liothyronine): 6 T4 (Levothyroxin): 4
Smallest size T3 (Liothyronine): 0.02 mg T4 (Levothyroxin): 0.04 mg
Largest size T3 (Liothyronine): 0.1 mg T4 (Levothyroxin): 0.2 mg
Price from (per bottle) T3 (Liothyronine): 20 EUR T4 (Levothyroxin): 32 EUR
Price up to (per bottle) T3 (Liothyronine): 155 EUR T4 (Levothyroxin): 115 EUR

Values from the sizes and catalogue prices on this page, without Express and discounts.

Half-life compared

How quickly do they break down?

Share left after one dose, calculated from the half-lives in the lexicon

T3 (Liothyronine)~24 hoursT4 (Levothyroxin)~7 days
Half-life = 50 %
Day 14 after the dose
T4 (Levothyroxin)25 %
T3 (Liothyronine)< 0.1 %
ProductHalf-lifeDay 7Day 14Day 28
T4 (Levothyroxin)~7 days50 %25 %6.3 %
T3 (Liothyronine)~24 hours0.8 %< 0.1 %< 0.1 %

Simplified model without an absorption phase, half-lives from the TPD lexicon.

Feature T3 (Liothyronine) T4 (Levothyroxin)
Category Cutting Cutting
Subcategory Thyroid Thyroid
Form Tab Tab
Price range 20 - 155 EUR 32 - 115 EUR
GLP-1 No No

Quick reference

What both have in common

  • Same subcategory: Thyroid - addressed via overlapping mechanisms.
  • Same main category: Cutting / Cutting

This page is a high-level comparison for community discussion only. Refer to the linked detail pages for full descriptions, risk profiles and peer-reviewed studies. Not medical advice.

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