GLP-1 Retatrutide
- Form
- Vial
- Sizes
- 5mg, 6mg, 10mg, 12mg, 15mg, 20mg, 24mg, 30mg, 40mg, 50mg, 60mg
- Price (10-pack)
- 160 - 816 EUR
- Class
- GLP-1
Product Comparison
Retatrutide vs Tirzepatide
Tirzepatide versus the next-gen tri-agonist Retatrutide (GLP-1 + GIP + Glucagon). Retatrutide has greater fat-burning potential in research models.
GLP-1 
GLP-1 Tirzepatide
- Form
- Vial
- Sizes
- 5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg, 100mg, 120mg
- Price (10-pack)
- 100 - 800 EUR
- Class
- GLP-1
By the numbers
Number of sizes Retatrutide: 11 Tirzepatide: 10
Smallest size Retatrutide: 5 mg Tirzepatide: 5 mg
Largest size Retatrutide: 60 mg Tirzepatide: 120 mg
Price from (10-pack) Retatrutide: 160 EUR Tirzepatide: 100 EUR
Price up to (10-pack) Retatrutide: 816 EUR Tirzepatide: 800 EUR
Values from the sizes and catalogue prices on this page, without Express and discounts.
Half-life compared
How quickly do they break down?
Share left after one dose, calculated from the half-lives in the lexicon
Retatrutide~6 daysTirzepatide~5 days
Half-life = 50 %
Day 12 after the dose
Retatrutide25 %
Tirzepatide18.9 %
| Product | Half-life | Day 7 | Day 14 | Day 28 |
|---|---|---|---|---|
| Retatrutide | ~6 days | 45 % | 19.8 % | 3.9 % |
| Tirzepatide | ~5 days | 38 % | 14.4 % | 2.1 % |
Simplified model without an absorption phase, half-lives from the TPD lexicon.
Level
Level with regular doses
Each dose adds to what is left of the last one until a plateau forms. Values relative to the first dose, simplified model, no dosing information.
Retatrutide: one dose per week, 7 days between dosesLexicon: Once weekly (subcutaneous)
Peak 1.8×Trough 0.8×
Day 21 · 4. dose
1.73× of the first dose
1.73× of the first dose
Plateau
from Day 21
96 % of the plateau after dose 4
Peak
1.8×
of the first dose
Trough
0.8×
before the next dose
Tirzepatide: one dose per week, 7 days between dosesLexicon: Once weekly (subcutaneous)
Peak 1.61×Trough 0.61×
Day 21 · 4. dose
1.58× of the first dose
1.58× of the first dose
Plateau
from Day 21
98 % of the plateau after dose 4
Peak
1.61×
of the first dose
Trough
0.61×
before the next dose
| Feature | Retatrutide | Tirzepatide |
|---|---|---|
| Category | GLP-1 | GLP-1 |
| Subcategory | GLP-1 & Fat Loss | GLP-1 & Fat Loss |
| Form | Vial | Vial |
| Price range | 160 - 816 EUR | 100 - 800 EUR |
| GLP-1 | Yes | Yes |
Quick reference
What both have in common
- Same subcategory: GLP-1 & Fat Loss - addressed via overlapping mechanisms.
- Same main category: GLP-1 / GLP-1
This page is a high-level comparison for community discussion only. Refer to the linked detail pages for full descriptions, risk profiles and peer-reviewed studies. Not medical advice.
