LGD-3033, product photo
SARMs

LGD-3033

SARMs

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At a glance

LGD-3033 by the numbers

The key figures from our lexicon.

Full lexicon entry

For research and educational purposes only. Values from the TPD lexicon, sources linked there.

There is no lab analysis for LGD-3033 yet. Vote for itAll lab analyses

Knowledge

Everything about LGD-3033

FAQ

Frequently asked

Sources for every answer: lexicon entry

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LGD-3033 or LGD-3303?

Both mean the same molecule. The studies use LGD-3303, the PubChem database lists both spellings under one entry. No study has been published under the name LGD-3033.

Has LGD-3033 been studied in humans?

No. As of 26 October 2026 ClinicalTrials.gov lists no trial with LGD-3303. All data come from three rat studies from 2009 and 2010.

What did the rats show for muscle and prostate?

In castrated rats the levator ani muscle grew above normal while the prostate never exceeded half of its normal weight, even at high amounts. This held whether swallowed or given by continuous infusion. The prostate tissue even held more compound than the muscle, so the preference arises at the receptor itself.

What is known about bone?

In female rats with bone loss after removal of the ovaries, bone density and mineral content rose at cortical and cancellous sites, as did muscle weight. Together with the osteoporosis drug alendronate the effect was at least as good as either alone and better at some sites.

What about the libido study?

LGD-3303 crosses the blood-brain barrier and is not converted to estrogen. In sexually experienced female rats it strengthened the preference for males, in naive animals the preference fell. An androgen receptor blocker cancelled the effect.

What is in SARM products from the internet?

In an analysis of 44 SARM products bought online only 52 percent contained any SARM at all. 39 percent contained another unapproved drug, 25 percent substances not on the label and only 41 percent had a matching amount.

Which side effects are known?

For LGD-3303 in humans none, because there is no human study. For the related SARM LGD-4033 the phase 1 study measured a drop in testosterone and HDL. A case report describes severe liver injury. Whether this applies to LGD-3303 is unknown.

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