This information is for research and educational purposes only. No medical recommendations. Products are not approved for human use. For health questions, consult a doctor.

Lexicon

Muscle & performance

Anadrol (Oxymetholone)

The strongest oral mass steroid - brutal gains, lots of water, very liver-loading.

1 min read 2 sources Titration Updated June 2026
Class
Oral anabolic (17a-alkylated, DHT derivative)
Use
Oral, 1x per day
Half-life
about 8-9 hours
WADA
banned (anabolic)

Getting started

Typical dosing (research context)

Per-day figures in mg, oral. 17a-alkylated - strongly liver-loading. Short cycles.

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What is Anadrol?

Anadrol (Oxymetholone, A50) is one of the strongest oral mass steroids. It delivers very fast, large gains in strength and weight but comes with a lot of water retention and, as a 17a-alkylated substance, is strongly liver-loading. Clinically oxymetholone is approved to treat anemia.

This information is for research and educational purposes only. No medical advice.

How it works

Oxymetholone activates the androgen receptor and strongly raises protein synthesis and erythropoiesis - hence the clinical use in anemia. It does not aromatize but still has estrogen-like effects (water retention, gyno risk) via another pathway, which is why classic aromatase inhibitors do not help here.

Use and dosing

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What the research shows

Oxymetholone has a real clinical history as an anemia drug. The AAS pharmacology (Kicman 2008, Hartgens & Kuipers 2004) classes the fast mass and strength gains of oral 17a-alkylated steroids.

Side effects

  • Liver: 17a-alkylated, strong - short cycles, liver support.
  • Water/gyno: estrogen-like effects despite no aromatization - classic AIs do not help.
  • Blood pressure: rises markedly from water retention.
  • Lipids: HDL drops strongly.
  • HPTA suppression - PCT topic.

Storage

Store dry and cool, protected from light. Out of reach of children.

Evidence

Sources

  1. 1 Pharmacology of anabolic steroids - comprehensive review. Kicman, Br J Pharmacol, 2008
  2. 2 Effects of androgenic-anabolic steroids in athletes. Hartgens & Kuipers, Sports Med, 2004

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