What is boldenone cypionate?
Boldenone cypionate is boldenone with a cypionate ester attached. Boldenone itself is testosterone with an extra double bond between the first and second carbon atoms, chemically 1-dehydrotestosterone. The compound is better known as the undecylenate, which comes from veterinary medicine under the brand name Equipoise.
The cypionate is the shorter of the two esters. The active compound in the body is the same, it is simply released faster from the depot in the muscle. In the range, boldenone cypionate comes as an oily injectable solution at 200 mg/ml.
This information is for research and educational purposes only. No medical advice.
How it works
Boldenone binds to the androgen receptor and, like other anabolic steroids, increases protein synthesis and nitrogen retention in muscle. Its signature is a marked stimulation of blood formation: the share of red blood cells (hematocrit) rises. This is often linked to more endurance and a stronger pump, but it also thickens the blood.
The extra double bond slows down aromatase. Boldenone is therefore converted to estrogen less than testosterone, in practice about half is the figure usually quoted. That does not make it free of estrogenic effects. The 5-alpha reduced form of boldenone is dihydroboldenone (DHB, 1-testosterone), which has its own entry as a separate product.
Gains on boldenone are considered slow and fairly moderate. Many users also report a clearly increased appetite. Solid human data on the profile are scarce, so the picture relies on general steroid pharmacology and animal data.
Where it acts
Where boldenone acted in studies
Tap a point or a card. Colour = androgen receptor, grey = observed. Almost everything from animal studies or reviews of anabolic steroids in general.
- Skeletal muscle
Binding to the androgen receptor, muscle building like other anabolic steroids (review)1
AR - Blood
Anabolic steroids stimulate red blood cell production (review, general)2
Observed in trials - Liver
Liver enzymes and blood lipids rose, HDL fell (rats, undecylenate)6
Observed in trials - Kidney
Urea, creatinine and uric acid rose (rats, undecylenate)6
Observed in trials - Heart
Heart heavier, markers of heart muscle damage and oxidative stress raised (rats)7
Observed in trials - Hormone control
Thyroid hormones fell, TSH rose, inflammation markers rose (rats, 8 weeks)4
Observed in trials
Known targets1
Compound PubChem CID 71314193: one described target, Target of all anabolic steroids, no separate mechanism recorded for boldenone in ChEMBL.
- Gene
- AR
- UniProt
- P10275
- ChEMBL
- CHEMBL1871
- Action
- Target of all anabolic steroids, no separate mechanism recorded for boldenone in ChEMBL
Cypionate or undecylenate?
Both products deliver the same active compound, only the ester differs. The undecylenate is a very long ester with a half-life of about 14 days. The cypionate is shorter: for testosterone the prescribing information gives about 8 days, for boldenone cypionate itself there is no human measurement.
- Blood levels: with the cypionate, levels rise faster and also drop faster after stopping.
- Active content: the shorter ester weighs less. By calculation, 1 mg of cypionate holds about 0.70 mg of boldenone, 1 mg of undecylenate about 0.63 mg.
- Frequency: two injections per week keep levels stable, with the undecylenate one is often enough.
- Build-up: boldenone still builds slowly, the cypionate only shortens the time until blood levels plateau.
Comparison
Boldenone in different forms
Boldenone with a short and a long ester, in blends and the related compound DHB, as stated in the TPD lexicon. Tap a card to open its entry.
Simplified: the ester sets how fast the compound leaves the depot, not what it does. None of these forms has been studied in humans. 109
Use and dosing
Dosing
Dosing, titration and syringe
Loading the dosing information …
- Getting started and stepping up, drawn as a staircase
- Units on the U-100 syringe for every step
- How long one vial lasts
Injection
Boldenone cypionate is usually injected intramuscularly, into the glutes, thigh or shoulder. With long esters subcutaneous use is possible too, but no more than about 0.5 ml should go into one spot. At 0.75 to 1.5 ml per dose, intramuscular is therefore usually more practical.
- Draw up with a thicker needle, inject with a thinner one (23G to 25G).
- Disinfect the rubber stopper and the injection site with alcohol first, use every needle only once.
- Inject slowly and rotate sites regularly.
- Never share a vial. Case reports of abscesses and hepatitis almost always trace back to non-sterile technique or shared vials.
What the research shows
Boldenone is mainly a veterinary compound. A review of testosterone, boldenone and nandrolone in horses describes decades of use for muscle building, while noting that the evidence on its effects is thin even in animals (Dirikolu, J Vet Pharmacol Ther 2023). There are no controlled human studies on either the undecylenate or the cypionate.
The general pharmacology of anabolic steroids is well described: binding to the androgen receptor, the role of aromatase and 5-alpha reductase and the typical side effects (Kicman, Br J Pharmacol 2008). For athletes, a review summarizes effects on strength, body composition, lipids, hormones and the liver (Hartgens and Kuipers, Sports Med 2004).
Animal data show that the effects reach beyond muscle. In a rat study with boldenone undecylenate over 8 weeks, inflammatory markers rose, thyroid hormones fell and TSH increased (El Deib, Int Immunopharmacol 2021). These are high doses in animals and not directly transferable, but they are a reason to keep an eye on blood work.
Study results
What the trials measured
Interactive: switch tabs, tap points, show or hide arms. Arms are named relative to each other, no dosing advice.
How much boldenone is in the ester10
Share of the compound in the mass, calculated from the molar masses in PubChem
Molar masses: boldenone 286.4, cypionate 410.6, undecylenate 452.7 g/mol. How fast levels rise and fall has not been measured for boldenone cypionate in humans.
Infections after steroid injections in the literature5
Share of the 14 described cases, all anabolic steroids, not only boldenone
Literature review from 1999 of all case reports. The authors consider the infections avoidable with education and sterile technique. There were no studies measuring the risk.
Research status
Where the research stands
ClinicalTrials.gov lists no trial with boldenone, neither as cypionate nor as undecylenate. As of 25 Oct 2026. 9
- Preclinical Used in horses for decades, plus animal studies
- Phase 1 no registered trial
- Phase 2 no registered trial
- Phase 3 no registered trial
- Approval not yet
So far there is no registered trial in humans. 9
Side effects
- Hematocrit: the key issue with boldenone. Thicker blood raises the risk of thrombosis and strains the heart. Measure regularly.
- Blood pressure: rises in many users, partly because of the higher hematocrit.
- Estrogen: weaker than with testosterone, yet water retention or gynecomastia are still possible in predisposed users.
- Lipids: HDL drops and the lipid profile shifts unfavorably.
- Natural production: is suppressed. Without a testosterone base, low libido and low drive are likely. PCT becomes a topic afterwards.
- Androgenic: acne and hair loss in predisposed users.
- Other: strong appetite, at higher doses some report restlessness or anxiety.
Boldenone is on the WADA prohibited list and remains detectable in testing long after the last injection.
Storage
Store the oily solution at room temperature and away from light, ideally in the original box. Do not put it in the fridge: in the cold the compound can crystallize. If crystals do form, warm the vial in your hand or in warm water and swirl it until the solution is clear again. Keep out of reach of children.