This information is for research and educational purposes only. No medical recommendations. Products are not approved for human use. For health questions, consult a doctor.

Lexicon

Equipoise (Boldenone Undecylenate)

The slow building steroid - mild gains, increased appetite, EPO-like effect.

1 min read 11 sources

Glass vial with golden oil and a black TPD label on a white podium, next to it a long chain of glossy blue 3D atoms with a ring structure, symbolic image for Boldenone Undecylenate
Preclinical · not approvedLab tested in the shop

Summary

At a glance

Sources checked on 26 Oct 2026

Half-life in horses
123 hours

Median after intramuscular injection, absorption half-life 8.5 hours; not measured in humans5

Liver marker ALT in rats
+192 %

8 weeks, compared with the control group (191.97% in the full text)1

HDL cholesterol in rats
-41.2 %

same study, LDL rose by 140.1%1

Sperm motility
60 %

Rats after 8 weeks, control group 87%2

Human trials in the registry
0 trials

no trial with boldenone on ClinicalTrials.gov, as of 25 Oct 202610

  • Boldenone Undecylenate is boldenone, i.e. testosterone with an extra double bond, with a very long undecylenate ester. In the USA it is approved as a veterinary drug for horses, not for humans.119
  • In horses the half-life after an intramuscular injection had a median of 123 hours. It has not been measured in humans.5
  • In a rat study liver and kidney markers as well as LDL rose clearly after 8 weeks while HDL fell by 41 percent. Liver and kidneys showed tissue damage.1
  • The body's own hormone axis is suppressed: in rats LH and FSH fell, sperm count and motility dropped and the share of misshapen sperm rose.2
  • There are no controlled human studies; reviews of anabolic steroids describe the effects typical for the class. Everything here is the state of research, not a recommendation.8710
Profile

Updated June 2026

How long does it stay in the body?

Share left after one dose, calculated with a half-life of ~14 days

Half-life ~14 days
After 28 days: 25 %
Day 14 · 50 %Day 28 · 25 %Day 42 · 12.5 %Day 70 · 3.1 %

Simplified model without an absorption phase, half-life from the TPD lexicon.

Class
Testosterone derivative

very long undecylenate ester

Use
Intramuscular or subcutaneous

1x per week

Half-life
about 14 days
WADA
banned

anabolic

Sizes
4 sizes

200mg/ml, 300mg/ml, 600mg/ml …

Contents 13 sections
  1. At a glance
  2. What is Equipoise?
  3. How it works
  4. Use and dosing
  5. What the research shows
  6. Research status
  7. Side effects
  8. Storage
  9. PCT / after coming off
  10. Related compounds
  11. FAQ
  12. Glossary
  13. Sources

What is Equipoise?

Equipoise (Boldenone Undecylenate, EQ) is a testosterone derivative with an extra double bond and a very long undecylenate ester. It builds slowly and mildly, is known for its appetite-increasing effect and a marked increase in red blood cells (EPO-like, more endurance/pump). Originally from veterinary medicine.

This information is for research and educational purposes only. No medical advice.

Comparison

Boldenone and relatives

Related steroids at the same receptor, as described in the TPD lexicon. Tap a card to open its entry.

How it works

Boldenone activates the androgen receptor and markedly raises erythropoiesis (red blood cell formation). It aromatizes mildly (about half as much as testosterone). Gains are slow but qualitatively "clean" and well retained.

Where it acts

Where boldenone acted in experiments

Tap a point or a card. Grey = observed in animal studies, blood from a review of the drug class.

  1. Pituitary

    LH and FSH fell in rats2

    Observed in trials
  2. Testes

    Sperm count and motility fell, more misshapen sperm (rat)2

    Observed in trials
  3. Liver

    ALT and AST rose, tissue damage (rat)1

    Observed in trials
  4. Kidney

    Urea and creatinine roughly doubled (rat)1

    Observed in trials
  5. Heart

    Relative heart weight and LDL rose, HDL fell (rat)3

    Observed in trials
  6. Body weight

    More weight gain and carcass yield (rabbit)4

    Observed in trials
  7. Blood

    Anabolic steroids stimulate erythropoietin and red cells according to a review8

    Observed in trials

Known targets8

Compound PubChem CID 11954310: one described target, Agonist like all anabolic steroids, no mechanism entry of its own in databases.

Androgen receptor
Gene
AR
UniProt
P10275
ChEMBL
CHEMBL1871
Action
Agonist like all anabolic steroids, no mechanism entry of its own in databases
Glossy blue 3D molecules leave a large glass droplet and attach to light blue transparent fibre strands, on the right a honeycomb-like glass structure
The long ester releases the compound slowly from the depot. Symbolic image.

Use and dosing

Dosing

Dosing, titration and syringe

Loading the dosing information …

  • Getting started and stepping up, drawn as a staircase
  • Units on the U-100 syringe for every step
  • How long one vial lasts
Glass vial with golden oil and a black TPD label, next to it a disposable syringe and a blank desk calendar on a white table
Symbolic image.

What the research shows

Boldenone is primarily veterinary; human studies are scarce. The AAS pharmacology (Kicman 2008, Hartgens & Kuipers 2004) describes the properties as a mildly aromatizing testosterone derivative.

Study results

What the trials measured

Interactive: switch tabs, tap points, show or hide arms. Arms are named relative to each other, no dosing advice.

Liver and kidney markers in rats1

Change after 8 weeks compared with the control group in percent

Liver marker ALT1
With boldenone undecylenate +192%
Liver marker AST1
With boldenone undecylenate +100%
Urea1
With boldenone undecylenate +103%
Creatinine1
With boldenone undecylenate +98%

Full-text values 191.97, 99.97, 103.01 and 98.19 percent, rounded in the chart. Liver and kidneys showed tissue damage under the microscope. Animal study, not tested in humans.

Blood lipids in rats1

Change after 8 weeks compared with the control group in percent

LDL cholesterol1
With boldenone undecylenate +140.1%
Total cholesterol1
With boldenone undecylenate +55.5%
Triglycerides1
With boldenone undecylenate +44.9%
HDL cholesterol1
With boldenone undecylenate -41.2%

Full-text values 140.14, 55.53, 44.93 and 41.21 percent, rounded in the chart. A second rat study also found more LDL, less HDL and a higher relative heart weight.

Sperm after 8 weeks2

Share in percent, group means (8 rats each)

Motile sperm2
Control group 87.0%
With boldenone undecylenate 60.0%
Misshapen sperm2
Control group 17.2%
With boldenone undecylenate 40.8%

Values from the full-text table (misshapen 17.24 and 40.82 percent, rounded). Sperm count, LH, FSH and testis weight relative to body weight also fell.

Transparent blood vessel full of red blood cells on a light background
The data come almost entirely from animal studies. Symbolic image.

Research status

Where the research stands

Boldenone Undecylenate is a veterinary drug. There is no registered human trial. As of 25 Oct 2026. 10

  1. Preclinical Rats, rabbits and horses
  2. Phase 1 no registered trial
  3. Phase 2 no registered trial
  4. Phase 3 no registered trial
  5. Approval not yet
Not approved for humans. Approved in the USA as a veterinary drug for horses (21 CFR 522.204), not for horses intended for human consumption.9

So far there is no registered trial in humans. 10

Side effects

  • Hematocrit: the marked EPO effect can thicken the blood - monitor regularly.
  • Estrogen: mildly aromatizing, AI if needed.
  • HPTA suppression: PCT topic.
  • Some report increased anxiety/restlessness at high doses.

Storage

Store the oil solution at room temperature, protected from light - no fridge needed. Out of reach of children.

Four glass vials with golden oil on a white shelf, next to them a folded light blue cloth
Oil solution at room temperature and protected from light, no fridge needed. Symbolic image.

Related

Related compounds

Same receptors or blends with Equipoise (Boldenone Undecylenate): all in the TPD lexicon.

FAQ

Common questions about Equipoise (Boldenone Undecylenate)

Short answers, each backed by the sources below.

Is Boldenone Undecylenate approved?

Only for animals. In the USA it is approved as an injection for horses, as an aid for debilitated horses when weight, hair coat or general condition should improve. Horses intended for human consumption must not receive it. There is no approval for humans and no trial on ClinicalTrials.gov (as of 25 October 2026).910

How long does one injection last?

This has not been measured in humans. In horses the half-life after an intramuscular injection had a median of 123 hours and absorption from the depot 8.5 hours. The long undecylenate ester makes the compound leave the oil slowly.5

What do animal studies show on liver, kidney and blood lipids?

In a rat study the liver markers ALT rose by 192 and AST by 100 percent after 8 weeks, urea and creatinine roughly doubled. LDL rose by 140 percent, HDL fell by 41 percent. Under the microscope liver and kidneys showed tissue damage. A second rat study found more LDL, less HDL and a heavier heart relative to body weight.13

What happens to the hormone axis and fertility?

In rats LH, FSH and testosterone inside the testes fell after 8 weeks. Only 60 instead of 87 percent of sperm were motile, 41 instead of 17 percent were misshapen. In rabbits the share of the testes in body weight fell. Reviews of anabolic steroids describe that natural hormone production can stay disturbed for months after stopping.248

Does boldenone raise red blood cells?

A review of anabolic steroids describes that they can stimulate erythropoietin and red cell production and affect haemoglobin. There are no controlled human data on this for boldenone specifically. That is why the entry advises having haematocrit checked regularly.8

How is boldenone broken down in the body?

In a doping research study men received oral boldenone. Their urine contained boldenone itself and nine breakdown products, more than 95 percent of them as stable conjugates. Doping control uses this pattern as evidence.6

Glossary

Terms explained briefly

Dotted words in the text open these explanations directly.

ALT and AST
Liver enzymes in the blood. If they rise, it points to stressed or damaged liver cells.
Androgen receptor
Protein inside the cell that androgens bind to. Genes are then read, for example for muscle building.
Aromatization
Conversion of an androgen to estrogen by the enzyme aromatase.
Creatinine
Breakdown product from muscle that the kidneys excrete. Higher levels can point to weaker kidney function but also rise with muscle mass.
Erythropoiesis
Formation of red blood cells in the bone marrow, driven by the hormone erythropoietin (EPO).
Haematocrit
Share of red blood cells in the blood. If it rises a lot, the blood gets thicker.
Half-life
Time after which only half of the compound is left in the blood.
Hormone axis (HPTA)
Hypothalamus, pituitary and testes together control the body's own testosterone production. Anabolic steroids from outside suppress this axis.
LH and FSH
Pituitary hormones. LH drives testosterone production in the testes, FSH drives sperm production.
PCT
Post cycle therapy, the phase after stopping in which natural hormone production is meant to restart.
Undecylenate ester
Very long acid chain attached to the compound. It makes it oil-soluble and releases it slowly from the depot.

Practice

PCT / after coming off

Anabolic substances suppress the body's own testosterone production in the research context. Anyone who comes off a cycle (rather than running it continuously) typically uses a post-cycle therapy (PCT) to restart the natural axis (HPTA).

The standard scheme in the research/literature context combines a SERM (tamoxifen and/or clomifene, alternatively enclomiphene) over roughly four weeks, optionally preceded by HCG to re-sensitise the testes before the SERM block. An aromatase inhibitor (anastrozole/exemestane) belongs more to on-cycle estrogen control than to the PCT itself.

Tip: order the PCT items together with the cycle so they are already on hand when you come off.

This information serves research and educational purposes only. Not medical advice.

Evidence

Sources

Show all 11 sourcesHide sources 8 Studies1 Trial registry2 Database checked 26 Oct 2026

Studies

  1. Liver and kidney in rats on boldenone undecylenate

    Behairy et al., Frontiers in Pharmacology, 2021

    Checked 26 Oct 2026 via doi.org, Crossref, PubMed, PMC (Volltext)
  2. Testes, hormones and sperm in rats

    Behairy et al., Antioxidants, 2020

    Checked 26 Oct 2026 via doi.org, Crossref, PubMed, PMC (Volltext)
  3. Heart and blood lipids in rats

    Tousson et al., Oxidative Medicine and Cellular Longevity, 2018

    Checked 26 Oct 2026 via doi.org, Crossref, PubMed, PMC (Volltext)
  4. Growth, hormones and carcass yield in rabbits

    Mohammed et al., Polish Journal of Veterinary Sciences, 2016

    Checked 26 Oct 2026 via doi.org, Crossref, PubMed
  5. Pharmacokinetics of boldenone in horses

    Soma et al., Journal of Veterinary Pharmacology and Therapeutics, 2007

    Checked 26 Oct 2026 via doi.org, Crossref, PubMed
  6. Breakdown of boldenone in humans

    Schänzer und Donike, Biological Mass Spectrometry, 1992

    Checked 26 Oct 2026 via doi.org, Crossref, PubMed
  7. Review of the pharmacology of anabolic steroids

    Kicman, British Journal of Pharmacology, 2008

    Checked 26 Oct 2026 via doi.org, Crossref, PubMed
  8. Review: effects and side effects of anabolic steroids in athletes

    Hartgens und Kuipers, Sports Medicine, 2004

    Checked 26 Oct 2026 via doi.org, Crossref, PubMed

Trial registry

  1. Search on ClinicalTrials.gov

    ClinicalTrials.gov, U.S. National Library of Medicine

    Checked 26 Oct 2026 via ClinicalTrials.gov API v2

Database

  1. Approval as a veterinary drug in the USA (21 CFR 522.204)

    Electronic Code of Federal Regulations, Title 21, § 522.204

    Checked 26 Oct 2026 via eCFR-API
  2. Structure of Boldenone Undecylenate in PubChem

    PubChem, U.S. National Library of Medicine (CID 11954310)

    Checked 26 Oct 2026 via PubChem

In the shop

Equipoise (Boldenone Undecylenate) in the catalog

Sizes, prices and shipping times are on the product page.

To the product