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Muscle & performance

Stanozolol Oil - Research Substance

Oily injection solution of the synthetic anabolic stanozolol (Winstrol), used in research contexts.

2 min read 9 sources

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Vial with blue cap and the black TPD label of Stanozolol Oil on a white podium, next to it a large blue 3D steroid molecule against a bright lab background
Formerly approved · from 1962 as a tablet, now off the market

Summary

At a glance

Sources checked on 26 Oct 2026

HDL cholesterol in 6 weeks
-33 %

11 weight lifters, tablets; with testosterone injections only -9%3

LDL cholesterol in 6 weeks
+29 %

same study; on testosterone LDL fell by 16%3

Until fibrinolysis rose
24 hours

one injection into the muscle, 12 healthy men, raised for one week1

Until liver values were normal
5 months

Case report: severe cholestasis after 2 months of injections2

With clearly lowered HDL
91 %

21 older people, tablets up to 6 months, back after stopping5

  • Stanozolol Oil is stanozolol as an oily solution for injection. Stanozolol is a synthetic, DHT-derived anabolic steroid with a 17-methyl group and acts on the androgen receptor.94
  • As an injection it has barely been studied: one study gave 12 healthy men a single 50 mg dose into the muscle. Fibrinolysis rose after 24 hours, after one month HDL had fallen and LDL had risen.1
  • The effect on blood lipids is the best documented: in studies with tablets HDL fell by 33 to 53 percent and LDL rose by 21 to 29 percent. After stopping the values returned.345
  • The liver is the second focus. A case report describes severe cholestasis after two months of injections, while liver values stayed unremarkable in a long-term study with a low dose.26
  • According to ChEMBL stanozolol has been approved since 1962, as a tablet, but it is no longer on the market. Everything here is the state of research, not a recommendation.9
Profile

Updated June 2026

How long does it stay in the body?

Share left after one dose, calculated with a half-life of ~30 hours

Half-life ~30 hours
After 60 hours: 25 %
Hour 30 · 50 %Hour 60 · 25 %Hour 90 · 12.5 %Hour 150 · 3.1 %

Simplified model without an absorption phase, half-life from the TPD lexicon. The lexicon gives 1 to 1.5 days, we calculate with the middle.

Class
DHT-derived synthetic anabolic steroid
Use
Research substance

non-clinical

Half-life
Approx. 24-36 hours
Status
WADA banned since 1976

not approved

Sizes
50mg/ml

1 size in the shop

Contents 13 sections
  1. At a glance
  2. What is Stanozolol Oil?
  3. How it works
  4. Use and dosing
  5. What the research shows
  6. Research status
  7. Side effects
  8. Storage
  9. PCT / after coming off
  10. Related compounds
  11. FAQ
  12. Glossary
  13. Sources

What is Stanozolol Oil?

Stanozolol Oil is a sterile oily injection solution of stanozolol, a synthetic C-17 alkylated anabolic steroid derived from DHT. It is known under various trade names, including Winstrol and Stromba. It is on the WADA doping list. The oily formulation allows intramuscular injection for research purposes.

This information is for research and educational purposes only. No medical advice.

Comparison

One compound, three forms

Stanozolol and related DHT derivatives in the TPD lexicon, as described there. Tap a card to open its entry.

Tablet Winstrol (Stanozolol) AR Aqueous suspension Stanozolol Water - Research Substance AR
Oily solution Stanozolol Oil - Research Substance AR
Other DHT derivative, oil Masteron P (Drostanolone Propionate) AR

Simplified: all act on the androgen receptor. The form sets how fast the compound reaches the blood. 9

How it works

Stanozolol binds to the androgen receptor with moderate to high affinity. Unlike many other anabolics, it is weakly aromatizable and promotes 'dry' muscle gain with minimal water retention.

  • DHT-like androgen receptor activity
  • Weakly aromatizable (minimal estrogen conversion)
  • Promotes protein synthesis and nitrogen retention
  • HPTA suppression

Where it acts

One receptor, several organs

Tap a point or a card. Grey = seen in studies, mostly with tablets.

  1. Liver and blood lipids

    HDL fell, LDL rose, hepatic lipase was 123% higher3

    Observed in trials
  2. Blood and clotting

    Fibrinolysis raised after 24 hours, for one week; plasminogen for three weeks1

    Observed in trials
  3. Muscle and weight

    Weight gain similar to testosterone3

    Observed in trials
  4. Skin and hair

    Acne and increased hair growth in the long-term study6

    Observed in trials

Targets in the ChEMBL database9

Compound CHEMBL2079587: one recorded mechanism, agonist with direct binding to the human receptor.

Androgen receptor
Gene
AR
UniProt
P10275
ChEMBL
CHEMBL1871
Action
Agonist, direct binding
Two blue 3D steroid molecules resting in hollows of glassy, striated muscle fibres
Stanozolol binds to the androgen receptor, for example in muscle. Symbolic image.

Use and dosing

Dosing

Dosing, titration and syringe

Loading the dosing information …

  • Getting started and stepping up, drawn as a staircase
  • Units on the U-100 syringe for every step
  • How long one vial lasts
Stanozolol Oil vial with the black TPD label and a disposable syringe on a white surface
Oily solution for injection into the muscle. Symbolic image.

What the research shows

Stanozolol is better documented than newer anabolics. Studies in humans show anabolic effects with selective muscle gain and minimal water retention. Negative effects on the lipid profile (HDL reduction) are well documented. HPTA suppression occurs at clinically relevant doses.

  • Well-documented anabolic effects
  • Lipid dysregulation (especially HDL reduction)
  • Minimal estrogen-dependent side effects
  • HPTA suppression confirmed

Study results

What the trials measured

Interactive: switch tabs, tap points, show or hide arms. Arms are named relative to each other, no dosing advice.

Blood lipids after 6 weeks3

Change in percent, 11 weight lifters, stanozolol and testosterone one after the other (crossover)

HDL cholesterol3
Stanozolol, weight lifters (tablets) -33%
Testosterone as comparison (injection) -9%
HDL2 (subclass)3 on testosterone only HDL3 fell
Stanozolol, weight lifters (tablets) -71%
Apolipoprotein A-I3
Stanozolol, weight lifters (tablets) -40%
Testosterone as comparison (injection) -8%
LDL cholesterol3
Stanozolol, weight lifters (tablets) +29%
Testosterone as comparison (injection) -16%

Stanozolol as a tablet, testosterone as an injection at a higher amount. The authors attribute the difference to the route through the liver with 17-alkylated tablets. Hepatic lipase rose by 123 percent on stanozolol.

Blood lipids after 6 weeks4

Change in percent, 10 postmenopausal women with osteoporosis

HDL cholesterol4
Stanozolol, postmenopausal women (tablets) -53%
HDL2 (subclass)4
Stanozolol, postmenopausal women (tablets) -85%
HDL3 (subclass)4
Stanozolol, postmenopausal women (tablets) -35%
Apolipoprotein A-I4
Stanozolol, postmenopausal women (tablets) -41%
LDL cholesterol4
Stanozolol, postmenopausal women (tablets) +21%

Total cholesterol and triglycerides stayed the same, the LDL to HDL ratio rose from 2.5 to 6.8. All changes had reversed 5 weeks after stopping.

Glass knee joint model between Petri dishes, pipettes and a measuring tape on a white background
Most studies used tablets, there are barely any data on the injection. Symbolic image.

Research status

Where the research stands

The registry knows only one trial with stanozolol, as a tablet and with unknown status. None is registered for the injection. As of 26 Oct 2026. 8

  1. Preclinical Blood lipids and vessels in an animal model (rabbits)
  2. Phase 1 no registered trial
  3. Phase 2 no registered trial
  4. Phase 3 no registered trial
  5. Approval from 1962 as a tablet, now off the market
Approved from 1962 as a tablet: ChEMBL lists stanozolol with phase 4 as the highest phase and today as no longer on the market.9

The approval predates today's trial registries, so the register shows no current trial for this form. 8

Side effects

Stanozolol is associated with several significant side effects:

  • Unfavorable lipid profile (LDL increase, HDL decrease)
  • Hepatotoxicity from C-17 alkylation
  • Joint pain (paradoxically despite muscle gain)
  • HPTA suppression and testosterone decline
  • Androgenization effects (acne, hair loss)
  • Muscle tension and cramp tendency

Tolerability

Frequency in studies with stanozolol tablets

Out of 100 participants, how many had the event. Two small studies with 21 people each, both with tablets, none with injections.

91 of 100 Stanozolol (tablets)
Event Stanozolol (tablets)
HDL clearly lowered5 91%
Treatment-related symptoms6 48%

In the long-term study: hair growth, weight gain, menstrual changes, acne and mood changes, all receding with a lower dose. Five people had low HDL, two raised triglycerides, liver values showed no lasting abnormality. In the 6-month study liver values rose temporarily in some.56

Storage

Stanozolol Oil is best stored at room temperature, protected from light. A refrigerator is not required and can cause crystallization with this oil.

  • Room temperature (15-25°C)
  • Protected from light and heat
  • Do not refrigerate or freeze
  • Store in tightly sealed container
Four glass vials with golden oil on a white shelf, next to a folded light blue cloth
At room temperature, protected from light, not in the fridge. Symbolic image.

Related

Related compounds

Same receptors: all in the TPD lexicon.

Stanozolol Oil - Research Substance
Winstrol (Stanozolol) The same compound as a tablet Stanozolol Water - Research Substance The same compound as an aqueous suspension Anavar (Oxandrolone) Also 17-alkylated, as a tablet Masteron P (Drostanolone Propionate) DHT derivative as oil Primobolan E (Methenolone Enanthate) DHT derivative with a long ester Testosterone Enanthate Comparison in the blood lipid study

FAQ

Common questions about Stanozolol Oil - Research Substance

Short answers, each backed by the sources below.

What is the difference between Stanozolol Oil, the tablet and the suspension?

It is the same compound in three forms. Clinically stanozolol was used almost only as a tablet, from 1962 according to ChEMBL. As an oil or aqueous suspension it is injected into the muscle. For the injection there is only one small study with a single dose.91

Is stanozolol approved?

It was approved. ChEMBL lists stanozolol with first approval in 1962 as a tablet and today as no longer on the market. The trial registry lists only one study with tablets whose status is unknown. Everything here is the state of research, not a recommendation.98

What did the injection study show?

12 healthy men received a single 50 mg dose into the muscle. After 24 hours plasminogen activator was raised and stayed so for one week, plasminogen rose from day two for three weeks. One month after the injection HDL cholesterol had fallen while total and LDL cholesterol had risen.1

What happens to blood lipids?

That is the best documented effect. In weight lifters HDL fell by 33 percent in 6 weeks and LDL rose by 29 percent, on testosterone injections only minus 9 and minus 16 percent. In postmenopausal women HDL fell by 53 percent. In both studies values returned after stopping.345

How does stanozolol affect the liver?

Stanozolol is 17-alkylated, which strains the liver. A case report describes a 19-year-old who injected 50 mg every other day for two months: severe cholestasis with very high bilirubin, normal only 5 months after stopping. In a study with tablets liver values rose temporarily in some, in the long-term study they showed no lasting abnormality.256

Which side effects were seen with longer use?

In a study of 21 people who took stanozolol tablets for 20 to 40 years, 10 had treatment-related symptoms: increased hair growth, weight gain, menstrual changes, acne and mood changes. They receded with a lower dose and nobody had to stop.6

How does stanozolol act in the body?

According to ChEMBL stanozolol binds directly to the androgen receptor and activates it. It derives from DHT and carries a methyl group at position 17. Researchers linked the unfavourable lipid effects to such 17-alkylated tablets. Weight lifters gained weight on stanozolol similarly to testosterone, but testosterone suppressed their own hormones more.943

Glossary

Terms explained briefly

Dotted words in the text open these explanations directly.

17-alkylation
A methyl group at position 17 slows breakdown in the liver. The compound lasts longer but strains the liver.
Androgen receptor
Protein inside the cell that androgens bind to. Genes are then read, for example for muscle building.
Aromatisation
Conversion of an androgen to oestrogen by the enzyme aromatase. Stanozolol is barely converted.
Cholestasis
Bile congestion in the liver. Bilirubin rises, skin and eyes can turn yellow.
DHT
Dihydrotestosterone, a strong androgen. Stanozolol is chemically derived from it.
Fibrinolysis
The body's own dissolving of blood clots.
HDL cholesterol
The cholesterol that carries fat from the vessels back to the liver. A low level is considered unfavourable for the heart.
Hepatotoxicity
Harmful effect on the liver, for example bile congestion or raised liver values.
Hormone axis (HPTA)
Hypothalamus, pituitary and testes together control the body's own testosterone production. Anabolic steroids from outside suppress this axis.
LDL cholesterol
The cholesterol that can build up in vessel walls. A high level is considered unfavourable.
WADA
The World Anti-Doping Agency. What is on its list is banned in competitive sport.

Practice

PCT / after coming off

Anabolic substances suppress the body's own testosterone production in the research context. Anyone who comes off a cycle (rather than running it continuously) typically uses a post-cycle therapy (PCT) to restart the natural axis (HPTA).

The standard scheme in the research/literature context combines a SERM (tamoxifen and/or clomifene, alternatively enclomiphene) over roughly four weeks, optionally preceded by HCG to re-sensitise the testes before the SERM block. An aromatase inhibitor (anastrozole/exemestane) belongs more to on-cycle estrogen control than to the PCT itself.

Tip: order the PCT items together with the cycle so they are already on hand when you come off.

This information serves research and educational purposes only. Not medical advice.

Tamoxifen (Nolvadex) SERM, core of PCT View Clomid (Clomifen) SERM, core of PCT View Enclomiphene (Androxal) SERM alternative View HCG testicular restart before PCT View Arimidex (Anastrozole) aromatase inhibitor, on-cycle View Aromasin (Exemestane) aromatase inhibitor, on-cycle View

Evidence

Sources

Show all 9 sourcesHide sources 7 Studies1 Trial registry1 Database checked 26 Oct 2026

Studies

  1. Single injection: fibrinolysis and blood lipids in 12 healthy men

    Small et al., Thrombosis Research, 1982

    DOI 10.1016/0049-3848(82)90030-5 PMID 6891506
    Checked 26 Oct 2026 via doi.org, Crossref, PubMed
  2. Case report: severe cholestasis after stanozolol injections

    Stępień et al., Clinical and Experimental Hepatology, 2015

    DOI 10.5114/ceh.2015.51376 PMID 28856252
    Checked 26 Oct 2026 via doi.org, Crossref, PubMed
  3. Blood lipids on stanozolol and testosterone compared

    Thompson et al., JAMA, 1989

    DOI 10.1001/jama.1989.03420080085036 PMID 2915439
    Checked 26 Oct 2026 via doi.org, Crossref, PubMed (Titel, Heft und Seiten, Datensatz ohne DOI)
  4. HDL drop on stanozolol in postmenopausal women

    Taggart et al., Metabolism, 1982

    DOI 10.1016/0026-0495(82)90166-4 PMID 6813637
    Checked 26 Oct 2026 via doi.org, Crossref, PubMed
  5. Liver values and blood lipids on stanozolol, placebo-controlled

    Carson et al., International Journal of Lower Extremity Wounds, 2015

    DOI 10.1177/1534734614562276 PMID 25652757
    Checked 26 Oct 2026 via doi.org, Crossref, PubMed
  6. Safety of long-term stanozolol treatment

    Sloane et al., Journal of Allergy and Clinical Immunology, 2007

    DOI 10.1016/j.jaci.2007.06.037 PMID 17765757
    Checked 26 Oct 2026 via doi.org, Crossref, PubMed
  7. Stanozolol, blood lipids and vessels in rabbits

    Fogelberg et al., Scandinavian Journal of Clinical and Laboratory Investigation, 1990

    DOI 10.3109/00365519009089189 PMID 2247776
    Checked 26 Oct 2026 via doi.org, Crossref, PubMed

Trial registry

  1. Trials with stanozolol on ClinicalTrials.gov

    ClinicalTrials.gov, U.S. National Library of Medicine

    Checked 26 Oct 2026 via ClinicalTrials.gov API v2

Database

  1. Mechanism and approval in ChEMBL

    ChEMBL, EMBL-EBI (CHEMBL2079587)

    Checked 26 Oct 2026 via ChEMBL

In the shop

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