This information is for research and educational purposes only. No medical recommendations. Products are not approved for human use. For health questions, consult a doctor.

Lexicon

Muscle & performance

Masteron E (Drostanolone Enanthate)

The long-acting masteron variant - the same hardening steroid, injected less often.

1 min read 2 sources Titration Updated June 2026

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Class: DHT derivative (long enanthate ester)
Use: Intramuscular or subcutaneous, 2x per week
Half-life: about 5-7 days
WADA: banned (anabolic)

Getting started

Typical dosing (research context)

Per-week figures in mg, split across 2 injections. Long ester - same drostanolone as Masteron P.

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What is Masteron E?

Masteron E (Drostanolone Enanthate) is the same active molecule as Masteron P, just with a long enanthate ester. That means less frequent injections (2x per week instead of every other day) at the same effect - the dry, hardening cutting effect of a DHT derivative.

This information is for research and educational purposes only. No medical advice.

How it works

Identical to Masteron P: DHT derivative, no aromatization, weakly anti-estrogenic. Only the kinetics differ due to the longer ester.

Propionate vs enanthate

Masteron P (propionate): short, every other day, quickly controllable.
Masteron E (enanthate): long, 2x per week, more convenient.

Dosing

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What the research shows

As with Masteron P: historical anti-estrogenic use in breast cancer, general AAS pharmacology in Kicman (2008) and Hartgens & Kuipers (2004).

Side effects

Androgenic (DHT derivative) - hair loss in predisposed individuals, acne.
Can lower HDL.
HPTA suppression - PCT topic.
Barely any estrogen side effects.

Storage

Store the oil solution at room temperature, protected from light - no fridge needed. Out of reach of children.

Practice

PCT / after coming off

Anabolic substances suppress the body's own testosterone production in the research context. Anyone who comes off a cycle (rather than running it continuously) typically uses a post-cycle therapy (PCT) to restart the natural axis (HPTA).

The standard scheme in the research/literature context combines a SERM (tamoxifen and/or clomifene, alternatively enclomiphene) over roughly four weeks, optionally preceded by HCG to re-sensitise the testes before the SERM block. An aromatase inhibitor (anastrozole/exemestane) belongs more to on-cycle estrogen control than to the PCT itself.

Tip: order the PCT items together with the cycle so they are already on hand when you come off.

This information serves research and educational purposes only. Not medical advice.

Tamoxifen (Nolvadex) SERM, core of PCT Clomid (Clomifen) SERM, core of PCT Enclomiphene (Androxal) SERM alternative HCG testicular restart before PCT Arimidex (Anastrozole) aromatase inhibitor, on-cycle Aromasin (Exemestane) aromatase inhibitor, on-cycle

Evidence

Sources

1 Pharmacology of anabolic steroids - comprehensive review. Kicman, Br J Pharmacol, 2008
2 Effects of androgenic-anabolic steroids in athletes. Hartgens & Kuipers, Sports Med, 2004

Keep reading

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Masteron E (Drostanolone Enanthate) in the catalog

Sizes, prices and availability for research use. Straight from the lexicon to the product page.

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