What is GHK Basic?
GHK Basic is the GHK peptide (glycyl-histidyl-lysine) in its base form, so without the tightly bound copper ion that characterizes the GHK-Cu variant. GHK is an endogenous tripeptide associated with skin, collagen and tissue regeneration.
How it works
GHK readily binds copper in the body anyway and unfolds many of its effects through that: it stimulates the formation of collagen and other connective-tissue building blocks, supports skin regeneration and acts antioxidant. The base form can take up the body's own copper, in practice GHK and GHK-Cu are closely related.
What you need
- The GHK Basic vial (lyophilized powder).
- Bacteriostatic water, U-100 insulin syringes, alcohol swabs.
Reconstitution
Use the calculator above. A 50mg vial with 2ml water gives 25mg per ml. Just add the water to the vial and let it dissolve.
Dosing
Members only
Dosing recommendations are visible to logged-in members only. Logging in is free.
Injection
Subcutaneous into the subcutaneous fat. Disinfect the site, pinch a skin fold, rotate sites.
What the research shows
A detailed review (Pickart & Margolina, 2018) summarizes the regenerative and protective actions of GHK: promotion of collagen, skin regeneration, wound healing and antioxidant effects. Much of this is described in cell and animal models, for injectable use in humans the data is thinner.
Side effects
- Generally well tolerated, mainly local reactions at the injection site.
- Solid human data on injection are limited.
Storage
Before mixing the powder is robust, normal room temperature (around 20 to 25 degrees) is fine, ideally kept in the dark. After mixing, keep in the fridge (2 to 8 degrees), do not freeze. It stays good there for at least 8 to 10 weeks with barely any loss of potency, in practice considerably longer. Swirl or shake to mix, both are fine.